Juan Gallo Paramo
Staff Researcher
Juan Gallo is a Staff Researcher and PI in the Nanomedicine group at INL. His research interests focus on the combination of three different but highly complementary features for the treatment of human conditions: imaging, therapy and responsiveness. This combination enables precise management of diseases through the specific treatment of each condition, coupled with real-time monitoring of the disease evolution and response to treatment. To achieve this, we work heavily with magnetic nanomaterials and nanocomposites that allow us to use MRI for non-invasive diagnosis and monitoring and magnetic hyperthermia as direct therapy or as an external trigger in combinatorial treatment schemes. In terms of applications, we have a strong interest in immunomodulation, either in cancer (immunostimulation) or in autoimmune diseases and transplants (immunosuppression).
Juan Gallo obtained his PhD from the University of the Basque Country, working at CIC biomaGUNE under Prof. Penadés on developing molecular imaging probes. He then moved to the UK, where he spent four years at Imperial College London working for Profs. Long and Aboagye develop contrast agents for different medical imaging technologies such as MRI, PET, optical and ultrasound. He joined INL in 2015, initially as a Marie Curie CoFund fellow.
Selected Publications
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Targeted treatment of triple-negative-breast cancer through pH-triggered tumour associated macrophages using smart theranostic nanoformulations
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023 -
(Para)magnetic hybrid nanocomposites for dual MRI detection and treatment of solid tumours
CHEMICAL COMMUNICATIONS, 2020