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A new tool being developed at INL can explore electrical effects on cells

A new tool being developed at INL can explore electrical effects on cells

While we usually consider electronics as a fruit of human engineering, electrical signalling is also fundamental in biology, playing an essential role in cellular functions from neuronal communication and muscle contraction to cell migration, proliferation and differentiation. Electrical stimulation activating these biological functions is therefore also a powerful tool for both fundamental research and for therapeutic applications. Alar Ainla, research scientist at INL, in collaboration with the Life and Health Sciences Research Institute (ICVS) at the University of Minho, has developed a novel multi-channel in vitro electrical stimulator to help study these effects in a versatile and accessible way. Their work was published in BMC Biomedical Engineering. Cells can sense and respond to the electric fields. Exposure to an electric field changes the electrical potential across the cell membrane, influencing voltage-gated ion channels and calcium signalling, which can trigger nerve impulses, muscle contraction, and even long-term processes like synaptic plasticity, cell proliferation, and differentiation. In stem and neuronal cells, electrical stimulation can promote axon growth, enhance the expression of neuronal markers, and trigger the release of molecules that guide the differentiation of neighbouring cells. In other words, cells behave like tiny sensors and communicators, adjusting their internal processes in response […]

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Shedding light on ultrafast heat transport in graphene

Shedding light on ultrafast heat transport in graphene

Managing heat efficiently is one of the great challenges in the development of next-generation electronic and optoelectronic devices. At the nanoscale, energy moves in ways that defy classical descriptions of heat transfer. Houssem Rezgui, researcher from the Sotomayor research group at INL, has now provided new insights into how energy flows in graphene when excited with ultrafast laser pulses. Their work, published as a Letter in Journal of Physics D: Applied Physics, explores how electrons and vibrations in the lattice (known as phonons) interact in timeframes shorter than a trillionth of a second. Graphene, with its remarkable electronic and thermal properties, is an ideal platform for probing these processes. When struck by a femtosecond laser pulse, graphene enters a highly non-equilibrium state: electrons absorb the incoming energy almost instantly, and only afterward begin to share it with the lattice. Traditionally, this sequence has been described by the two-temperature model, which assumes that electrons and phonons equilibrate in a straightforward way. However, the INL researcher shows that reality is more complex. Using an extended temperature model, Rezgui revealed that different phonon branches respond at distinct timescales, with longitudinal acoustic phonons playing a key role in energy absorption and redistribution. Strikingly, their […]

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Magnetic nanowires take hydrogen production to the next level

Magnetic nanowires take hydrogen production to the next level

As the world looks for cleaner ways to produce energy, green hydrogen (fuel made from water and renewable electricity) is gaining attention as a promising solution. To make green hydrogen affordable and efficient, better catalysts are needed to speed up the chemical reactions involved. Researchers at INL – International Iberian Nanotechnology Laboratory have developed a new type of magnetic catalyst that could change the game. Their findings, recently published in ACS Nano, reveal how these magnetic nanowires efficiently catalyse the oxygen evolution reaction, a key reaction in hydrogen production from water. The research team led by Yury Kolen’ko created cobalt ferrite (CoFe2O4) nanowires using a technique called electrospinning, which forms ultra-thin fibres by using an electric field to draw solid threads from a liquid solution; imagine sugar being spun into cotton candy, but at the nanoscale. By precisely controlling the calcination temperature, the team transformed the fibres into nanowires with excellent magnetic properties, critical for their catalytic performance. Why does magnetism matter? The oxygen molecules, which are formed during the water-splitting process, have a special triplet spin state. When the catalyst is magnetic, it can influence the spin alignment of the reaction intermediates, guiding the reaction to proceed faster and […]

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Eco-friendly sensor developed at INL enables rapid detection of pharmaceutical contaminants in water

Eco-friendly sensor developed at INL enables rapid detection of pharmaceutical contaminants in water

Pharmaceutical waste in water sources is becoming a growing environmental concern. Among the most common pollutants are paracetamol and 4-aminophenol, a related compound that can appear as a contaminant or breakdown product. These substances persist in urban wastewater and surface waters, potentially harming aquatic ecosystems and human health. Detecting them accurately and efficiently is crucial for environmental protection and risk management. Researchers at INL from Espiña’s research group have designed an innovative electrochemical sensor that can simultaneously detect both pharmaceuticals at very low concentrations. The sensor uses carbon screen-printed electrodes modified with specially functionalised carbon nanofibers, which enhance sensitivity and selectivity. This study published in the journal Sensing and Bio-Sensing Research, describes a solution for portable, cost-effective, and environmentally friendly tool for water quality monitoring. Traditional methods for identifying pharmaceutical contaminants often rely on complex laboratory techniques such as chromatography and spectrometry. While highly precise, these require expensive equipment, trained personnel, and time-consuming sample preparation, limiting their use for routine or on-site testing. In contrast, electrochemical sensors like the one developed by the INL team led by Raquel Queirós, provide rapid, real-time results with minimal costs. The research team compared different transducer materials, finding that carbon-based ones performed better than […]

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Cristiana Alves: Revealing the Invisible Through Materials Science

Cristiana Alves: Revealing the Invisible Through Materials Science

Meet Cristiana Alves, Facility Lead at the Electron Microscopy and X-Rays (EMX) Facility at INL. With a lifelong curiosity for how things work and a deep passion for uncovering the unseen, Cristiana’s journey into materials engineering and nanotechnology has been driven by both precision and wonder. From exploring bioactive coatings for dental implants during her PhD to working in one of the most advanced electron microscopy facilities in the Iberian Peninsula, she combines technical excellence with a commitment to discovery. At the heart of her work is a drive to understand materials at their most fundamental level, and to help others do the same. Can you tell us a bit about your path, your main area of work, and the importance of your work?Since I was a child, I have always loved to explore and discover things in nature, get to know how things work, and why they work in such a way. I also loved math because for me, math is simple; there are no doubts or misinterpretations. This combination brought me to an engineering course (materials engineering).While pursuing my master’s, I naturally became passionate about research and science, and I pursued a PhD to study nanomaterials for biomedical applications. When you […]

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Science, Innovation and Society: INL attends the Science 2025 Meeting

Science, Innovation and Society: INL attends the Science 2025 Meeting

Between the 9th and 11th of July, the International Iberian Nanotechnology Laboratory was represented at Encontro Ciência 2025, Portugal’s largest science and technology meeting. This year, the event took place at the NOVA SBE Campus in Carcavelos, Lisbon, and centred around the theme “Science, Innovation and Society”. Part of the “Science, Technology, Innovation” exhibition, INL was present throughout the three-day event, fostering engagement with policymakers, researchers, students, and the broader public, in a clear celebration of the importance of science in the public sphere. Professor Ado Jório, INL’s Deputy Director-General, participated in the opening session, where several key figures opened the event by addressing priorities in science and innovation. First, Nuno Piteira Lopes, Vice-President of the Cascais City Council, and Dr Isabel Rocha, Vice-Rector of Nova University, welcomed participants, stressing the contemporary nature of societal concerns and how science and innovation contribute to their resolution, while Dr Vera Aldeias, Commissioner of Encontro Ciência 2025, highlighted the increasing need to reduce bureaucracy. Rosalia Vargas reinforced the role of the Ciência Viva network and Professor Madalena Alves, President of the Foundation for Science and Technology (FCT), emphasised the impact of digital tools, the agency’s support for research careers, gender equality, and its ongoing restructuring. Finally, Dr Helena Canhão, Secretary of State for Science and Innovation, outlined goals to reform the fragmented science system, boost industrial innovation, continue U.S. partnerships, and enhance funding opportunities in Portugal, […]

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INL Joins Global Dialogue on Innovation and IP at WIPO General Assemblies

INL Joins Global Dialogue on Innovation and IP at WIPO General Assemblies

The International Iberian Nanotechnology Laboratory (INL) is proud to participate as an observer at the 66th session of the World Intellectual Property Organization (WIPO) General Assembly, held from 8 to 17 July 2025 at WIPO Headquarters in Geneva, Switzerland. This participation reaffirms INL’s commitment to international cooperation in science and its active contribution to the global dialogue on innovation, intellectual property, and technology for sustainable development. The 66th session brought together more than 1,600 delegates representing all 194 WIPO member states, including over 40 ministers and deputy ministers, and nearly 100 heads of national patent offices. The assembly served as a vital forum for exchanging expertise, sharing achievements, and shaping global strategies to enhance intellectual property systems in support of innovation-driven growth. During the opening session, WIPO Director General Daren Tang welcomed the Federated States of Micronesia, WIPO’s newest member state. He highlighted the resilience and dynamism of the global innovation ecosystem, noting that more than 40 intellectual property applications are filed every minute worldwide. INL’s presence in Geneva underscores the importance of aligning nanotechnology and advanced science with international policy frameworks, ensuring that emerging technologies contribute meaningfully to global sustainable development goals.

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Empowering the Next Generation: INFRACHIP Research Accelerator Kicks Off at INL

Empowering the Next Generation: INFRACHIP Research Accelerator Kicks Off at INL

The International Iberian Nanotechnology Laboratory (INL) is proud to host an edition of the INFRACHIP Research Accelerator, a high-impact, short-term training programme designed to introduce early-career researchers to the cutting-edge technologies and facilities available through the INFRACHIP network. Over the course of two and a half days, 6 to 8 selected participants, PhD students and early-stage postdoctoral researchers—will gain hands-on exposure to advanced nanofabrication and nanocharacterization techniques. The immersive programme blends lectures by INL experts with live demonstrations inside two of INL’s state-of-the-art Research Core Facilities: the Micro and Nanofabrication (MNF) and Electron Microscopy and X-Rays (EMX). Participants will explore fundamental processes in micro- and nanofabrication such as deposition, patterning (optical and electron beam lithography), and etching (RIE). The programme also includes a deep dive into structural and chemical analysis techniques, including: + Transmission Electron Microscopy (TEM): Imaging, diffraction, and spectroscopy + Focused Ion Beam – Scanning Electron Microscopy (FIB-SEM) + X-Ray Photoelectron Spectroscopy (XPS) With a strong emphasis on practical training, participants will enter INL’s cleanroom and microscopy labs to directly observe and engage with the equipment and processes discussed in the lectures. This initiative is part of the broader INFRACHIP vision to democratize access to nanoelectronics infrastructure and strengthen the European research ecosystem. By sponsoring these researchers, INFRACHIP aims to accelerate their scientific progress […]

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INL Workshop on Medical Devices Helps Shape EU Policy Milestone in Advanced Materials

INL Workshop on Medical Devices Helps Shape EU Policy Milestone in Advanced Materials

Just months after INL hosted a high-level workshop on Advanced Innovative Materials for Medical Devices, the momentum generated in Braga has culminated in a major policy advancement: At its second meeting, the High Level Technology Council for Advanced Materials, held in Brussels last week, expanded its industry priorities to include advanced materials for medical devices. This marks a significant recognition of the groundwork of the subgroup tasked with examinign this option discussed at INL in April, where European leaders, policymakers, and innovators gathered to explore the transformative potential of advanced materials in health materials and associated technologies. “The inclusion of materials for health in the form of medical devices is a strategic priority for Europe,” said Dr Clivia Sotomayor Torres, Director-General of INL, who chaired the subgroup with support form Dr Lorena Diéguez, research group leader at INL.  She added: “it’s a testament to the power of collaborative dialogue and scientific foresight.” From INL to Brussels: Driving the Agenda Forward Organised under the High Level Technology Council for Advanced Materials, an initiative of the European Commission launched in late 2024, the April 2025 workshop at INL served as a strategic forum under the Council’s Subgroup on Future Priorities. It brought together key European figures including Irene […]

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