Alfaro-Moreno Group
The group was launched with the support of an ERA-Chair grant entitled SiNfONiA – Safety in Nanomaterials & Nanotechnology. The overall aim of SiNfONiA is to boost RTD activities in the nanosafety arena and strengthen the research and innovation potential of INL.
Research Lines:
- Organ-on-a-chip technology to evaluate the safety of nanomaterials used on products that could get in contact with the skin or the respiratory tract.
- Epigenetics and in vitro/in vivo bridging models to evaluate the safety of different nanomaterials and pollutants.
- Toxicology and immunotoxicology of nanomaterials using sensors and high-throughput technologies.
- In silico evaluations using QSAR, QSPR, QSTR, machine learning and life cycle assessment.
Projects
Publications
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Decoding the conformational binding of drug mixtures on ovalbumin: An integrated multimodal network.
International Journal of Biological Macromolecules, 2024Differential DNA methylation and metabolite profiling of Atlantic killifish (Fundulus heteroclitus) from the New Bedford Harbor Superfund site
ECOTOXICOLOGY, 2024 -
Ambient black carbon particles in human ovarian tissue and follicular fluid
ENVIRONMENT INTERNATIONAL, 2023Revealing the binding dynamics between catanionic surfactants and lysozyme: A synergistic computational approach coupled with experimental validation.
Journal of Molecular Liquids, 2023Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials
TRENDS IN BIOTECHNOLOGY, 2023A Nano-QSTR model to predict nano-cytotoxicity: an approach using human lung cells data
PARTICLE AND FIBRE TOXICOLOGY, 2023In Vitro Cell Transformation Assays: A Valuable Approach for Carcinogenic Potentiality Assessment of Nanomaterialsned...
International Journal of Molecular Sciences, 2023Titanium dioxide nanoparticles affect osteoblast-derived exosome cargos and impair osteogenic differentiation of human mesenchymal stem cells
BIOMATERIALS SCIENCE, 2023To be defMixture and individual effects of benzene, toluene, and formaldehyde in zebrafish (Danio rerio) development: Metabolomics, epigenetics, and behavioral approaches
Environmental Toxicology and Pharmacology 97: 104031, 2023The Effects of Titanium Dioxide Nanoparticles on Osteoblasts Mineralization: A Comparison between 2D and 3D Cell Culture Models
NANOMATERIALS, 2023The system of self-consistent models based on quasi-SMILES as a tool to predict the potential of nano-inhibitors of human lung carcinoma cell line A549 for different experimental conditions
DRUG AND CHEMICAL TOXICOLOGY, 2023 -
To be defined...
, 2021