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Researchers Inspire Young Minds at Schools

As part of the European Researchers’ Night initiative, researchers visited several schools in the summer camp program in Tadim-Braga to promote science and engage young students. These visits are part of the ongoing efforts to celebrate science and bring it closer to citizens, aligning with ERN’s 2024-2025 theme of “Science for Global Challenges.” July 4: Engaging the Young MindsOn July 4, a team of INL researchers, including Catarina Moura, Carlos Honrado, Adriana Carneiro, Bernardo Nogueira, Maria Relvas, and Tiago Moura, prepared different experiences for students of EB1 Tadim, EB2,3 Tadim, and Alfacoop schools. 45 students participated and built on their knowledge and interest in scientific topics. The activities conducted were designed to illustrate how science can address major global and European challenges in environmental, economic, and social sustainability. July 18: Continuing the Journey of DiscoveryOn July 18, researchers João Henriques, João Rodrigues, Lurdes Gonçalves, Diana Oliveira, Mariam Debs, Carlos Rosário, and Catarina Moura prepared different experiences, once again, for students of EB1 Tadim, EB2,3 Tadim, and Alfacoop schools. Students, aged between 4 to 14, participated in interactive sessions that sparked their curiosity and enthusiasm for science. These activities were tailored to suit the varied age groups, ensuring that each student […]

Filipa Lebre: Exploring the Frontier of Nanosafety

Filipa Lebre is a Research Fellow in the Nanosafety Research Group at INL, and her research focuses on the complex interactions among the immunological system and different organs, using novel technologies and in-house developed systems. Filipa has a background in Pharmaceutical Sciences and holds a PhD in Pharmaceutical Technology from the Faculty of Pharmacy, University of Coimbra, focused on the development and optimization of a polymeric nasal vaccine against hepatitis B to be used for mass immunization. She moved to Ireland during her postdoc to conduct her research at the interface between biomaterial and immunology, studying key aspects of immunomodulation by a relevant spectrum of materials with applicability in the regenerative medicine field. Could you share with us your professional trajectory and what inspired you to embark on a career in nanosafety? I’m very curious by nature and always had this passion and interest in science. When I did my degree in Pharmaceutical Science, I was fortunate enough to find a teacher who was working in the vaccine field and made me realize how I could use my passion to impact millions of lives. That was when I started to work with nanoformulations. I obtained my PhD in formulation development, […]

Can we cut the energy consumption of current AI technologies?

As artificial intelligence, commonly referred to as AI, becomes increasingly integrated into various aspects of our daily lives, the energy demands of AI systems continue to rise. Despite AI being inspired by the human brain, it is significantly less energy efficient because most tasks are implemented on computer hardware that is not specifically tailored for this purpose. The human brain remains an exemplar of energy-efficient computation, a standard that modern technology strives to replicate. INL researchers are studying advanced materials and devices aimed at revolutionising AI systems. Carlos Rosário, ERA fellow at INL (Marie Skłodowska-Curie actions (MSCA)), focuses his research on reducing the substantial energy consumption required by current AI technologies. Carlos’ work is grounded in the field of neuromorphic computing, which seeks to mimic the brain’s intricate network of neurons and synapses using artificial equivalents. The goal is to create an electronic brain capable of performing complex computations with minimal energy use. One of the key areas of Carlos Rosário’s research is the exploration of 3D topological insulators for novel electronic devices. These cutting-edge materials exhibit unique properties: while they are insulators and do not conduct electricity through their bulk, their surfaces behave like metals, allowing for efficient electrical […]

Secretary of State for Science Visits INL, Showcasing Key Projects and Innovations

Prof. Dr Ana Paiva, Secretary of State for Science, visited INL – International Iberian Nanotechnology Laboratory today. This visit provided an exceptional platform for INL to present its ongoing projects and significant achievements in the field of science and technology. The presence of Prof. Dr. Paiva underscored the crucial role of INL’s work and its far-reaching impact on the broader scientific community. Prof. Dr. Clivia M. Sotomayor Torres, INL Director-General, welcomed Prof. Dr Paiva and provided an insightful overview of INL’s mission and accomplishments. This introduction set the stage for a series of detailed presentations and discussions that highlighted INL’s prominence in both the national and European research landscapes. Presentation Highlights: Secretary of State’s visit to INL was a testament to the laboratory’s dedication to innovation, excellence, and its significant contributions to the field of science and technology. This visit not only highlighted INL’s achievements but also reinforced the importance of continued support and investment in scientific research and development. Text and Photography by Gina Palha

Breakthrough technology for cancer diagnostics

INL researchers are part of the consortium behind BIOCELLPHE, a pioneering project focused on advancing cancer diagnostics and personalised medicine. This innovative European-funded project is at the forefront of scientific and technological innovation, introducing a groundbreaking technology for identifying proteins as diagnostic biomarkers at the single-cell level. This new approach offers multiplexing capabilities, portability and enhanced sensitivity. Alexandra Teixeira, research fellow at the Medical Devices group, highlights that “BIOCELLPHE is pioneering the use of engineered bacteria to recognise and bind with high specificity to protein targets on the surface of circulating tumour cells, or CTCs, which are key players in cancer metastasis.” This specific binding of engineered bacteria to CTCs subsequently triggers the production of molecules (Raman reporters), which can be detectable with high sensitivity using surface-enhanced Raman scattering (SERS). More specifically, SERS uses plasmonic nanoparticles to enhance Raman signals, allowing ultrasensitive analysis and detection at the single molecule level. The pathological role of CTCs in cancer metastasis is not completely understood due to the lack of effective analytical tools and remains an area that needs further exploration. BIOCELLPHE addresses this gap by developing new tools for the phenotypic identification of CTCs at the single-cell level, with high-throughput and multiplexing […]

A miniaturised model of human digestion to advance therapies and nutritional products

INL researchers have made a significant breakthrough in the development of reliable in-vitro digestion models. This ‘digestion-chip’ promises to revolutionise the way new oral formulations are tested, offering a more accurate, efficient, and cost-effective alternative to current models. Traditional in-vitro digestion models often fail to replicate the complex dynamics of the human gastrointestinal tract. They either lack critical digestive processes or require large volumes of samples and reagents, which can be challenging when dealing with nanomaterials. The INL’s innovative ‘digestion-chip’ addresses these limitations with its miniaturised design and advanced features. The coordinator of the study Catarina Gonçalves explains, “the Food Processing and Nutrition research group proposes a miniaturised digestion system based on incubation chambers integrated into a polymethylmethacrylate device. This solution incorporates key dynamic features of human digestion while maintaining low complexity and using small volumes of samples and reagents”. The digestion-chip features gradual acidification (the stepwise addition of enzymes and simulated fluids during the gastric phase) and controlled gastric emptying. These capabilities are essential for replicating the intricate environment of the human stomach and intestines. The research team’s experimental results indicate that “the ‘digestion-chip’ successfully replicates the established static digestion INFOGEST protocol”. Moreover, “the semi-dynamic digestion kinetics observed with […]

INL hosted a two-day gathering focused on Functional Layered Materials

Between June 18 and 19, INL hosted a two-day action promoted by FUNLAYERS – a twinning initiative led by INL. The programme brought together stakeholders from academia, the private sector, and policymakers to engage with two actions. On the first day, participants delved into insightful talks and lively discussions on spin-based applications and energy storage. The exchange of ideas led to a fruitful discussion on the latest developments and future perspectives for Functional Layered Materials. The second day was dedicated to a hands-on session focused on writing a sound proposal under the MCSA Postdoctoral Fellowships. The workshop gathered young researchers, grant experts, and experienced scientists in a vibrant and insightful ideation exercise. These actions aimed to establish the foundations for facilitating knowledge sharing and cooperation between relevant actors in the field.

Open Innovation Testbeds gathered at IndTech 2024 to discuss a collaborative strategy for the commercialisation of services

Around 30 representatives from 16 Open Innovation Testbeds (OITB) projects gathered in Namur, Belgium, on June 6th for the workshop “A Collaborative Strategy for the Commercialization of OITB Services.” This event coincided with IndTech 2024, where the session “Open Innovation Test Bed: A New Kid on the Block” took place on June 5th. Key takeaways included identifying collaboration areas for joint service portfolios in specific markets, steps to achieve these goals, and the challenges ahead. We also discussed the medium-term vision of a unified OITB ecosystem, aligned with future technology infrastructures in advanced materials. By identifying synergies, sharing resources, and addressing industry needs—particularly for SMEs and startups—the final aim is to support a more competitive industry that drives sustainable growth and employment in Europe.

Academia Senior visits INL

Last week, on June 4th, INL had a special visit from the “Academia Sénior” of Braga*. A total of 26 students, the oldest one being 90 years old, walked through the corridors of INL to learn about our short institutional history and the meaning of the famous phrase “There’s plenty of room at the bottom” from Dr. Richard Feynman. During their visit to INL, as part of their course “Memoirs and Autobiographies”, the beloved visitors had the opportunity to learn about the nanoscience behind both, technologies under development as well as existing technologies that are already touching people’s day-to-day activities. As our society embraces technological advancements, it is essential to recognise that curiosity knows no age limits. Elderly individuals remain keenly interested in new technologies and equipment, appreciating their potential towards new discoveries, to enhance quality of life and foster connections. As taxpayers, they have a right to transparency—understanding how investments in these innovations are made. Aiming to extend inclusiveness beyond the workforce, this visit reinforces the responsibility to open science to everyone, including those who have retired but still seek engagement and learning opportunities. This ensures that technological progress benefits all, regardless of age, promoting lifelong learning and active […]

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