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Nano Circus: the amazing experience of arts & science

Nano Circus: the amazing experience of arts & science

Last Friday evening, INL hosted the Nano Circus, an extraordinary event that combined nanotechnology and circus arts, in a dazzling show of creativity and collaboration. Nano Circus showcased the culmination of a transformative artistic residency by the Equilibrium Social Circus team at INL. The Director General of INL Professor Clivia Sotomayor, took the stage to officially inaugurate the celebration, emphasising INL’s commitment to making the wonders of nanotechnology accessible to diverse communities. In July, the Equilibrium Social Circus team was invited to visit INL for an exciting artistic residency, fostering the exchange of knowledge. Sara Leite, project coordinator at Projecto Homem, gave a few words before the show “Equilibrium Social Circus is a social project dedicated to preventing behavioural issues in adolescence through Social Circus, an innovative approach merging circus arts and social intervention to act as a catalyst for psychosocial transformation”. These students weren’t passive observers – they were the architects of the Nano Circus. With guidance from their mentor Rodolfo Correia, they explored INL’s laboratories, delving into the microscopic world of nanotechnology and interacting with scientists. INL researchers Adriana Carneiro, Andrea Gouvêa, José Loché, and Duarte Mota, shared their scientific expertise, and the Equilibrium Social Circus team shared […]

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Nanotechnology uncovering the hidden secrets of cancer

Nanotechnology uncovering the hidden secrets of cancer

Metastasis, the spreading of cancer cells to other parts of the body, contributes to 9 out of 10 cancer-related deaths. However, the intricate mechanisms triggering this process remain a mystery. 3DSecret is on a mission to change that. The European consortium 3DSecret, coordinated by INL researchers from the Medical Devices research group, is approaching metastasis in a new way, focusing on single cells and aiming to uncover hidden patterns that can predict and forecast how cancer spreads. “By studying individual circulating tumour cells, or CTCs, 3DSecret hopes to transform how cancer is diagnosed and/or treated, making significant strides in clinical sciences”, says Miguel Xavier, technical coordinator of the 3DSecret project. In response to this challenge, 3DSecret has outlined specific objectives. At the forefront is the development of the ‘3Dsecret-chip,’ a sophisticated tool designed to facilitate the controlled creation of 3D cancer cell models from individual cells. This innovative approach promises reproducibility and precision, enhancing one’s ability to examine the details of cancer cell behaviour. Furthermore, 3DSecret is incorporating ‘SERS metabolomics profiling’, an advanced technology providing continuous insights into the growth kinetics of these 3D cancer cell models. Sara Abalde-Cela, leader of the Medical Devices research group and coordinator of the […]

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Wrapping Up 2023: Research

Wrapping Up 2023: Research

2023 has been a busy year for the INL Community. This week we take a look at some of this year’s highlights and achievements regarding our projects, and the latest research developments. Even with all the changes, INL persisted in performing interdisciplinary research and deploying and articulating nanotechnology for the benefit of society addressing society’s grand challenges.  Here’s a comprehensive wrap-up of the key moments that defined the past 12 months. INL inaugurates state-of-the-art Cryo-Electron Microscope that helps to study new diseases Analysing biostructures down to the atomic level can help to study diseases such as Alzheimer’s or cancer, as well as to develop new therapies. This new type of investigation is now possible from Braga, thanks to the new electronic cryogenic microscope installed at INL – International Iberian Nanotechnology Laboratory. The acquisition of this equipment is part of the creation of the CryoEM-PT National Network, “an electron microscopy network for life and health sciences”, explains Paulo Ferreira, scientific coordinator of this initiative that opens doors to researchers and companies in Iberia, allowing easy access to state-of-the-art infrastructure and technologies. Read the full update >> ATLANTICLAM, brings Euro-native clam species from ‘farm to fork’ INL – International Iberian Nanotechnology Laboratory […]

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Solar energy solutions inspired by nature

Solar energy solutions inspired by nature

ADAPTATION is the new European-funded project, which involves collaborative efforts from Spain and Portugal. This Iberian consortium combines the scientific expertise from INL, Consejo Superior de Investigaciones Científicas (CSIC), University of Minho, and University of Vigo. ADAPTATION draws inspiration from nature, more precisely from photosynthesis. The project aims to develop an innovative technology to absorb solar energy for electricity generation while incorporating self-cooling capabilities to mitigate energy losses. Sara Núñez-Sánchez, researcher at the University of Minho and coordinator of the project, explains that “the survival of plants does not depend so much on the amount of energy they absorb but on how efficiently they transport that energy”. This mechanism is what the ADAPTATION project aims to mimic, creating a new concept for a solar energy conversion device. The efficiency of devices that convert energy into electricity, such as solar panels, tends to decrease as heat accumulates. “The integration of photovoltaic or solar energy capture technologies is incompatible with technologies that allow efficient temperature management”, says Pedro David García, a researcher at ICMM-CSIC. The Iberian team will focus on mimicking, at the molecular level, how natural photosynthetic tissues are organised to generate new materials at the nanoscale. “All the structures we […]

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Understanding quantum entanglement

Understanding quantum entanglement

INL researchers have recently published a scientific paper describing a new method to confirm the presence of quantum entanglement. Similar to electricity and magnetism, quantum entanglement is a natural phenomenon that plays a central role in the most fascinating aspects of quantum mechanics. Quantum entanglement is a peculiar and counterintuitive occurrence that describes the intricate connection between two subatomic particles, even when they are separated by large distances. Any alteration made to one of these particles will instantaneously impact the other, defying the conventional expectation that distance should limit such influences. The idea that quantum entanglement can be used as a resource is fundamental to fields like quantum computing, quantum sensing, and quantum communications. To make use of quantum entanglement, it is crucial to develop tools for investigating it, which can be particularly challenging at the nanoscale. INL researchers have recently described a new technique to identify quantum entanglement, by using state-of-the-art equipment – electron spin resonance using scanning tunnelling microscopy (STM). Joaquín Fernández-Rossier, Theory of Quantum Nanostructures research group leader, says that “our proposal adds a completely new functionality to STM, establishing a connection between quantum information and surface science”. This work was supported by the Quantum Portugal Initiative […]

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Solar-powered textiles in automotive innovation

Solar-powered textiles in automotive innovation

Exploring the integration of solar cells into textiles for the automobile industry presents an intriguing prospect. This innovation could extend to practical applications, such as using solar-charged fabrics to power electronic devices like phones, thereby enhancing the sustainability and functionality of future automotive designs. While textiles are primarily associated with clothing, they have a rich historical use in sailcloth, tents, and sacks. Leveraging textiles as substrates for solar cells could further expand their potential applications. However, the adoption of fabrics as photovoltaic substrates raises pertinent questions. Textiles must endure the necessary processing conditions to become photovoltaics; resulting solar textiles must withstand wear and tear, as well as washing and drying cycles. There might be a risk of solar cells compromising crucial physical or aesthetic features of textiles. Most commonly known photovoltaics typically consist of solar cells mounted on glass. However, their weight and fragility may pose challenges in certain applications. The exploration of lighter and more flexible solar cells presents potential advantages, including enhanced durability, cost-effectiveness, and resilience in harsh environments. “Integrating solar cells into textiles is technologically challenging,” explains Roma Raj, a researcher in the Nanochemistry research group. “A critical issue is the adhesion of thin photovoltaic films to […]

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Regeneration after spinal cord injury, a project financed by CaixaResearch Health Research 2023 Contest

Regeneration after spinal cord injury, a project financed by CaixaResearch Health Research 2023 Contest

Alar Ainla from INL and Nuno Silva from the Institute of Research in Life and Health Sciences (ICVS) at the School of Medicine (EMed) won the CaixaResearch Health Research 2023 award, an initiative promoted by the “la Caixa” Foundation. The awardees were granted a prize of around one million euros for a project on spinal cord injuries that is based on the creation of a new device and treatment in order to regenerate nervous tissue leading to functional gains. ICVS leads this unique project and will allow a close collaboration between both institutes that will enable the interaction between experts in biology and technology in an area where it will be possible to boost innovation and the development of advanced solutions for the regeneration of spinal cord injuries. The World Health Organization (WHO) estimates that, annually, there are between 40 and 80 cases of spinal cord injuries per one million inhabitants. Although the survival rate of these people has increased significantly in recent decades, this type of injury continues to cause neurological disorders with enormous repercussions on the lives of affected individuals. Although some treatments allow partial recovery of neuronal functions, taking advantage of an intrinsic property of the central […]

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Recent research reveals neuro-behavioural changes associated with exposure to diesel exhaust particles

Recent research reveals neuro-behavioural changes associated with exposure to diesel exhaust particles

Air pollution is known to increase the likelihood of neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease. However, the exact mechanism involved in this relationship remains poorly understood. Diesel exhaust particles stand out as a prominent air pollutant with proven human carcinogenic properties, posing significant health risks, especially in the context of neurodegenerative diseases. Nivedita Chatterjee, a researcher from the Nanosafety research group at INL, is studying how diesel exhaust particles affect neurodegeneration, i.e. the slow and progressive loss of neurons. The INL team found that exposure to diesel exhaust particles causes significant neuro-behavioural alterations. Ernesto Alfaro-Moreno, Nanofatey research group leader explains that “this research work was developed under the project iCare – one of the objectives of this EU-funded project is to develop an integrated model system that can characterise and predict the potential impact of nanomaterials on brain health, thereby preventing nanomaterials toxicity”. Nivedita adds “to establish these models, we use Caenorhabditis elegans, often referred to as C. elegans, which is a very small and transparent roundworm that has been extensively studied in the field of biology. The knowledge gained from these studies on C. elegans often has broader implications for understanding more complex organisms, including humans.” The […]

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Matryoshka-like MEMS accelerometer

Matryoshka-like MEMS accelerometer

Nowadays, MEMS (Micro-Electro-Mechanical Systems) accelerometers play a crucial role in various applications such as inertial navigation, earthquake detection, spacecraft guidance, geophysical sensing, and structural monitoring. These microfabricated structures offer advantages such as small size, lightweight, low cost, low power, and easy integration with semiconductor technology, making them widely adopted in different fields. Researchers at INL have recently published a study introducing a micromachining technique to create complex MEMS structures for multi-axis sensing. The developed sensor uses a capacitive open-loop operation and features a hierarchical design resembling matryoshka dolls. This design allows for simple fabrication and operation, making it suitable for structural monitoring systems. The sensor comprises a double proof-mass hierarchical design with separate electrode sets for in-plane differential measurements. It operates based on changes in capacitance resulting from accelerations in different directions – accelerations in the xx and yy directions affect the gap of the differential sensing electrodes, leading to a differential capacitance change, while zz acceleration affects non-differentially their overlapping area. To detect zz acceleration direction, out-of-plane parallel plates are added to the device using suspended metallic membranes. Inês Garcia, one of the authors of this study and a member of the IMiNa research group, explains that “the proposed […]

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